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It contains Tacrolimus which belongs to the group of medicines called Immunosuppressants. It is used to prevent graft rejection in patients undergoing organ transplantation. It can also be used to treat an ongoing graft rejection of the newly transplanted organ.

Pangraf 1.0mg capsules contain the active ingredient tacrolimus, a potent immunosuppressant belonging to the macrolide and calcineurin inhibitor class of drugs. Its primary use is in patients who have undergone organ transplants, such as a kidney, liver, or heart, to prevent the body's immune system from rejecting the new organ. It can also be used to treat ongoing organ rejection. By suppressing the body's immune response, Pangraf helps the body accept the transplanted organ as its own. 

Takfa 1 mg capsules contain tacrolimus, an immunosuppressant medication used primarily to prevent organ rejection in patients who have received a transplant of a kidney, liver, or heart. It is manufactured by Intas Pharmaceuticals Ltd.. Tacrolimus works by suppressing the body's immune system, which would otherwise recognize the new organ as a foreign body and attack it.